Insights for clinical and commercial therapy success

Increase the efficiency of the research process by organising, analysing and evaluating anonymised, relevant and high quality real-world data. Produce reliable and actionable insights to inform clinical decisions and policy-making.

Market access

Sizing the opportunity and hitting the market.
Spot market trends using a wide array of healthcare data filtered through our advanced analytical tools. Predict shifting demands based on the insights of our network of key opinion leaders. Stay informed with regular data updates.

Market sizing

Build an understanding of the prevalence and incidence of a specific disease. Learn about the level of adoption of current standard-of-care therapies. Size the gap of patients who are not yet treated or on a sub-optimal treatment. Estimate the market size and potential for a new therapy. Prepare for the launch of a new product for a planning and pricing strategy. Cascador provides different market sizing services, harnessing real-world data and therapy-specific expertise, to seize your opportunity.

Epidemiological study

Analyse the distribution patterns and determinants of health and disease conditions in a defined population. Understand the burdens of an illness in terms of incidence, prevalence and mortality. Investigate patient profiles applying a cross-sectional, case-control or cohort study approach. Cascador provides evidence-based epidemiological study services to better understand specific disease processes and their implications for therapies.

Managed entry and reimbursement

Prepare to enter the market with a new therapy. Build a convincing case for market approval and for reimbursement approval. Show therapy efficacy compared to alternative treatments. Prove continuous performance over time to retain reimbursement. Cascador Health provides all types of managed entry services to fuel your reimbursement file based on real-world evidence.

Health economics assessment

Evaluate how a new therapy compares against existing alternatives and the standard of care. Assess costs of therapy, quality of life, societal costs, patient outcomes and societal benefits in an integrated way. Foster value-based healthcare thinking. Cascador provides a data-driven health economics assessment and valuable insights for the strategic positioning and pricing of your novel therapy or technology.

Other design possibility

Toggles

Build an understanding of the prevalence and incidence of a specific disease. Learn about the level of adoption of current standard-of-care therapies. Size the gap of patients who are not yet treated or on a sub-optimal treatment. Estimate the market size and potential for a new therapy. Prepare for the launch of a new product for a planning and pricing strategy. Cascador provides different market sizing services, harnessing real-world data and therapy-specific expertise, to seize your opportunity.
Analyse the distribution patterns and determinants of health and disease conditions in a defined population. Understand the burdens of an illness in terms of incidence, prevalence and mortality. Investigate patient profiles applying a cross-sectional, case-control or cohort study approach. Cascador provides evidence-based epidemiological study services to better understand specific disease processes and their implications for therapies.
Prepare to enter the market with a new therapy. Build a convincing case for market approval and for reimbursement approval. Show therapy efficacy compared to alternative treatments. Prove continuous performance over time to retain reimbursement. Cascador Health provides all types of managed entry services to fuel your reimbursement file based on real-world evidence.
Evaluate how a new therapy compares against existing alternatives and the standard of care. Assess costs of therapy, quality of life, societal costs, patient outcomes and societal benefits in an integrated way. Foster value-based healthcare thinking. Cascador provides a data-driven health economics assessment and valuable insights for the strategic positioning and pricing of your novel therapy or technology.

Tabs

Build an understanding of the prevalence and incidence of a specific disease. Learn about the level of adoption of current standard-of-care therapies. Size the gap of patients who are not yet treated or on a sub-optimal treatment. Estimate the market size and potential for a new therapy. Prepare for the launch of a new product for a planning and pricing strategy. Cascador provides different market sizing services, harnessing real-world data and therapy-specific expertise, to seize your opportunity.
Analyse the distribution patterns and determinants of health and disease conditions in a defined population. Understand the burdens of an illness in terms of incidence, prevalence and mortality. Investigate patient profiles applying a cross-sectional, case-control or cohort study approach. Cascador provides evidence-based epidemiological study services to better understand specific disease processes and their implications for therapies.
Prepare to enter the market with a new therapy. Build a convincing case for market approval and for reimbursement approval. Show therapy efficacy compared to alternative treatments. Prove continuous performance over time to retain reimbursement. Cascador Health provides all types of managed entry services to fuel your reimbursement file based on real-world evidence.
Evaluate how a new therapy compares against existing alternatives and the standard of care. Assess costs of therapy, quality of life, societal costs, patient outcomes and societal benefits in an integrated way. Foster value-based healthcare thinking. Cascador provides a data-driven health economics assessment and valuable insights for the strategic positioning and pricing of your novel therapy or technology.

Clinical evidence

Robust studies to foster evidence and good clinical practices.
Advance medical research by addressing real-world problems. Improve decision-making and patient outcomes based on real-world data. Integrate insights from key healthcare experts and add new scientific insights by creating new data sets.

Outcome Measurement

Track outcomes of interventions based on pharmaceutical or medical device therapies. Establish a baseline, track patient-reported outcome and experience metrics, physician-reported outcomes, and define performance on the short-, mid- and long-term. Cascador provides services that foster evidence-based practices, to track and improve outcomes, manage patient conditions, mitigate patient risk and optimise therapeutic choices.

Therapy Efficacy Assessment

Measure outcome parameters in a structured and consistent manner at set intervals, and evaluate outcomes against internationally accepted guidelines. Stratify outcomes by lifestyle, demographics, treatment history, comorbidities, and biomarkers. Cascador offers services to assess the efficacy of therapies in real-world settings and show the robustness of therapeutic outcomes for different healthcare settings.

Therapy eligibility assessment

Apply established national and international therapy-specific eligibility criteria in clinical practice. Identify which patients can benefit from a therapy or indication based on the patient’s health profile, treatment history, comorbidities and the level of severity and control of the condition. Cascador provides services to establish the eligibility of a cohort of patients, based on clinical guidelines and current real-world data on patient conditions, to create awareness and guide patients to the most suitable therapy.

Study support services

Draw up or review a study protocol, select and onboard the most suitable sites and PIs, run clinical operations that render fast and compliant access to RWD, scrutinise and valorise datasets and harness data to generate meaningful evidence and insights. Cascador provides tailored support to address selected aspects of your study and deliver high-quality outcomes.

Full 360° study management

Shape, set up and run studies from A to Z. For phase 4 (post-market) prospective, retrospective and register-based RWD and RWE studies by Cascador Specialties, Cascador provides full 360° study management.

Full 360° Study Management

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Therapy adoption

Actionable insight to bride the evidence-practice gap.
Identify a therapy’s efficacy, which patients benefit most from it, and how the therapy is integrated into treatment regimes. Benchmark a therapy against its competitors and identify the barriers to advancing its adoption.

Patient journey and referral assessment

Understand how patients are referred to specialists by different physicians and for which specific treatment plan. Understand referral patterns and their drivers. Cascador Health helps make patient journeys and referral patterns transparent based on actual referral behaviour and real-world data.

Patient screening

Identify the most suitable patient profile for a specific therapy. Find patients who might benefit from specific treatment and assess them against eligibility criteria. Measure key parameters and routinely follow up or embed decision trees in your clinical practice. Cascador Health helps turn patient screenings into a structured process.

Patient engagement and education

Ensure patients are well informed about their health condition, treatment options and therapy. Engage patients for continued follow-up of their therapy, allowing physicians to (re)act swiftly as needed. Cascador Health provides services to educate patients and has patient education modules embedded in their patient app / e-proms solutions, to foster patient engagement and therapy success.

Physician engagement and education

Ensure physicians are well informed about the latest innovations, therapy alternatives, their potential and proven clinical effectiveness. Engage physicians to adopt technology that improves collaboration across specialities. Incentivise and involve physicians in knowledge sharing. Cascador Health offers physician engagement and education services, standalone or as part of a scientific study, to efficiently unlock physician-reported data, foster guideline adherence and involvement in research initiatives.

Adoption barrier assessment

Physician and patient preference for the current standard of care, financial and regulatory roadblocks, … many barriers prevent the swift adoption of new therapies. Overcome a lack of trust in new therapies or technologies by learning about habitual behaviours in prescription, limited exposure to or information about guidelines and the efficacy of novel therapies. Cascador Health offers services to identify, map and address these barriers in a structured way and helps foster therapy adoption.

Cascador specialties

Leading the way with real-world data and expertise in Respiratory.

Our expertise in Respiratory drives precision and innovation in every aspect of our services, ensuring superior outcomes for our clients. Our studies go beyond unlocking real-world data. Cascador focuses on generating clinical evidence and actionable insights that fuel decision-making by sponsors and accelerate market access and therapy adoption.

Through the acquisition and integration of Galenus Health, we have gained a deep therapeutic understanding of Respiratory and developed in-house capabilities to deliver research excellence. Furthermore, we surround ourselves with a network of Key Opinion Leaders, serving as a research advisory board to further shape our offering, design specific studies, and engage with top clinical centres.

Most research is delivered as part of a multi-year program and involves strategic partnerships with pharma companies and selected clinical centres from the top 200 hospitals worldwide. Together, we address the needs of sponsors on an ongoing basis. We deploy a combination of prospective and retrospective patient recruitment as needed and integrate data from various sources, including doctors and patients.

Our expertise in Respiratory drives precision and innovation in every aspect of our services, ensuring superior outcomes for our clients. Our studies go beyond unlocking real-world data. Cascador focuses on generating clinical evidence and actionable insights that fuel decision-making by sponsors and accelerate market access and therapy adoption.

Through the acquisition and integration of Galenus Health, we have gained a deep therapeutic understanding of Respiratory and developed in-house capabilities to deliver research excellence. Furthermore, we surround ourselves with a network of Key Opinion Leaders, serving as a research advisory board to further shape our offering, design specific studies, and engage with top clinical centres.

Most research is delivered as part of a multi-year program and involves strategic partnerships with pharma companies and selected clinical centres from the top 200 hospitals worldwide. Together, we address the needs of sponsors on an ongoing basis. We deploy a combination of prospective and retrospective patient recruitment as needed and integrate data from various sources, including doctors and patients.

CHRINOSOR

Driving evidence on biologics therapies.

Our current signature program is CHRINOSOR, the CHronic RhINOSinusitis Outcome Registry. Cascador has built the largest European outcome registry for patients with chronic rhinosinusitis with nasal polyps and runs a research program with three big pharma sponsors, each with a biologics therapy on the market for CRSwNP, and 15+ top clinical centres.

Together, we deliver real-world evidence on therapy efficacy, biologics therapy eligibility and prescription behaviours. The outcomes of this program include six scientific publications in 2024, presented by Cascador at leading congresses.

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